Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) technology has revolutionized modern prosthodontics by enabling precise, efficient, and predictable fabrication of dental restorations. The integration of digital workflows, intraoral scanning, virtual design, and automated manufacturing has significantly improved the accuracy, aesthetics, and longevity of prosthodontic treatments. CAD/CAM systems are widely used in the fabrication of crowns, bridges, veneers, implant-supported restorations, removable prostheses, maxillofacial prostheses, and complete dentures. This review explores the principles, components, clinical applications, advantages, limitations, and future directions of CAD/CAM technology in prosthodontics. A comprehensive review of current literature, clinical studies, and technological developments was conducted. Findings indicate that CAD/CAM systems improve treatment efficiency, reduce laboratory errors, enhance patient satisfaction, and provide superior restoration quality. Challenges remain regarding equipment costs, learning curves, and material limitations. The study concludes that CAD/CAM technology has become an indispensable component of contemporary prosthodontics and will continue to shape the future of digital dental rehabilitation.