Oral Candidiasis in Immunocompromised Patients

doi:N/A

Global Journal of Dental Specialty

2023, Volume 1, Issue 2 : 1-4

Research Article

Oral Candidiasis in Immunocompromised Patients

Sarah Mitchell

David Thompson

Emily Carter

Department of Oral Medicine and Oral Diagnosis, Global Dental Research Institute, London, United Kingdom

Department of Oral Pathology and Microbiology, International College of Dental Sciences, New York, USA

Department of Infectious Diseases and Clinical Research, European Medical Research Center, Berlin, Germany

Abstract

Oral candidiasis is one of the most common opportunistic fungal infections affecting immunocompromised individuals. It is primarily caused by Candida species, particularly Candida albicans, which normally exist as commensal microorganisms within the oral cavity. Alterations in host immunity, systemic diseases, prolonged antibiotic therapy, chemotherapy, radiotherapy, organ transplantation, and Human Immunodeficiency Virus (HIV) infection can predispose individuals to candidal overgrowth and infection. Oral candidiasis may significantly impair quality of life through pain, dysphagia, altered taste sensation, and nutritional deficiencies. Early diagnosis and appropriate treatment are essential to prevent complications and systemic dissemination. This review explores the epidemiology, pathogenesis, clinical manifestations, diagnostic approaches, management strategies, and future research directions regarding oral candidiasis in immunocompromised patients. The study highlights the importance of multidisciplinary care and emerging diagnostic technologies in improving patient outcomes.

Keywords

Oral Candidiasis

Candida albicans

Immunocompromised Patients

HIV

Oral Fungal Infection

Oral Medicine

Opportunistic Infection

Antifungal Therapy

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