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Global Journal of Dental Specialty
2023, Volume 1, Issue 1 : 1-6
Research Article
Salivary Biomarkers in Oral Disease Diagnosis
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1
Department of Oral Medicine and Diagnostic Sciences, Global Dental Research Institute, London, United Kingdom
2
Department of Oral Pathology and Microbiology, International College of Dental Sciences, New York, USA
3
Department of Biomedical Research and Molecular Diagnostics, European Institute of Clinical Medicine, Berlin, Germany
Abstract

Saliva has emerged as a promising diagnostic fluid due to its non-invasive collection, ease of handling, and rich composition of biological molecules. Salivary biomarkers offer significant potential for the early detection, diagnosis, prognosis, and monitoring of various oral diseases, including dental caries, periodontal disease, oral potentially malignant disorders, and oral squamous cell carcinoma. Recent advances in molecular biology, proteomics, genomics, transcriptomics, and metabolomics have enhanced the identification and validation of salivary biomarkers for clinical applications. This review explores the role of salivary biomarkers in oral disease diagnosis, discusses current diagnostic technologies, evaluates their clinical utility, and highlights future prospects in precision dentistry. The study concludes that salivary diagnostics may revolutionize oral healthcare by enabling rapid, accurate, and personalized disease management.

 

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